In order to reveal the evolution rules of supply chain network with the core of manufacturers, a kind of five-level local world network model was put forward. This model used the BA model and the multi-local world theory as the foundation, combined with the reality of network node generation and exit mechanism. First of all, the intrinsic characteristics and evolution mechanism of network were studied. Secondly, the topology structure and evolution rules of the network were analyzed, and the simulation model was established. Finally, the changes of network characteristic parameters were simulated and analyzed in different time step and different critical conditions, including nodes number, clustering coefficient and degree distribution, then the evolution law of the network was derived. The simulation results show that the supply chain network with the core of manufacturers has the characteristics of scale-free and high concentration. With the increase of time and the growth rate of the network nodes, the degree distribution of overall network approaches to the power-law distribution with the exponent three. The degree distribution of the network at all levels is different, sub-tier suppliers and retailers obey power-law distribution, suppliers and distributors obey exponential distribution, manufacturers generally obey the Poisson distribution.